City rankings
Largest Cities in South Carolina
Charleston ranks #1 in South Carolina for largest cities at 154,338.
This ranking orders all 50 qualifying South Carolina cities by population, computed from the named federal field or time-series described below. It is one of 9 transparent ranking lenses Areazine publishes for South Carolina, each answering one direct question from official data. Compare Charleston's standing against every other South Carolina city ranked below.
Data updated 2026-08-21
- 50
- Cities ranked
- 154,338
- #1 Charleston
- 10,530
- Lowest, Forest Acres
What this South Carolina ranking shows
According to the U.S. Census Bureau's American Community Survey (ACS) 5-year estimates, the CDC PLACES population-level health analysis, and the CMS Hospital Compare quality data, Areazine ranks U.S. cities across more than 19,000 incorporated places, census-designated places, and consolidated city-county governments. State-level city rankings combine these federal datasets to produce intra-state comparisons across demographics, economics, health outcomes, and hospital quality.
Charleston leads 50 South Carolina cities at 154,338, while Forest Acres sits at the bottom with 10,530 - a total spread of 143,808 on population. The top 5 occupy 55% of that range, indicating a wide separation between leaders and the rest of the field.
The median South Carolina city in this list sits at 23,796, 130,542 behind Charleston. See our methodology for ranking construction, data vintage, refresh cadence, and the federal upstream tables we join, and triangulate via the 8 other South Carolina rankings below, cities that lead on multiple lenses are the most robust signals.
Top 5 - Largest Cities
| Rank | City | population | Population |
|---|---|---|---|
| #1 | Charleston | 154,338 | 133K |
| #2 | Columbia | 139,643 | 142K |
| #3 | North Charleston | 119,913 | 108K |
| #4 | Mount Pleasant | 93,993 | 81K |
| #5 | Rock Hill | 75,259 | 72K |
Does population track with city size?
Largest Cities vs. population, top 25 ranked cities
Largest Cities 50
More South Carolina Rankings 8
Reading this South Carolina ranking responsibly
Single-metric rankings are useful precisely because they are honest about what they measure. A "highest income" ranking does not tell you that the top-ranked city is the best place to live in South Carolina; it tells you that, among cities of population ten thousand and above in South Carolina that have a published median household income field in the most recent American Community Survey five-year estimates, this city has the highest such value. That precise definition matters, because composite "best places" lists from real-estate marketing sites and lifestyle magazines often combine income with subjective weights on schools, walkability, and amenities, producing a score whose components are not disclosed and whose ordering is not reproducible. Areazine's editorial commitment is to keep the underlying field, source, and vintage visible so the reader can audit any rank in this list against the canonical federal record.
Cross-checking against other rankings is a useful sanity test. A city that appears in the top ten on three or more different rankings, for example, highest income, most educated, and lowest poverty, is showing a robust signal across multiple independent dimensions. A city that appears in the top ten on only one ranking and middling on the others is showing a narrower signal, often driven by a single statistical artifact (a small population pulling the per-capita measure, a recent acquisition spike inflating median home value, an outlier survey year). The other nine South Carolina rankings linked above provide that cross-check at zero extra effort.
Data Sources
Population and economic data from the Census Bureau American Community Survey (2024 5-year estimates). Health data from the CDC PLACES (2023). Ranking computations use U.S. Census Bureau reference geographies. Crime statistics, where referenced, originate from the FBI Uniform Crime Reporting program (also accessible via the Crime Data Explorer).
Read our methodology - how this data is sourced, computed, and verified.