Shortage of Dextrose Monohydrate 50% Injection

Drug Shortages medium FDA · · United States

The FDA has reported a current shortage of Dextrose Monohydrate 50% Injection due to increased demand, affecting some manufacturers' availability.

What this drug shortages alert tells you, and what most readers miss

This notice was issued by FDA on April 8, 2026 and geographically references United States. Its severity classification of "medium" signals how the issuing agency weighs the risk of harm if no action is taken — "critical" and "high" tier alerts typically carry direct consumer actions, while "medium" and "low" tend toward informational guidance or monitoring advisories. The category it belongs to — Drug Shortages — determines the regulatory framework behind it, which shapes what remedies (refunds, replacements, recalls, evacuations) are available to affected individuals and who holds statutory responsibility for enforcement.

Most readers skim an alert like this, check whether they are personally affected, and move on. The more useful lens is to read the alert as a data point about the issuing system: how quickly FDA detected the hazard, how precise the geographic or product-identifier scope is, and whether similar alerts have clustered in the same category or region in the last 90 days. Cluster patterns frequently precede a broader regulatory action — a single localized drug shortages advisory is isolated; three of them within a quarter often indicate a supply-chain, infrastructure, or seasonal driver that will keep producing notices until something structural changes.

For decision-making, Areazine pairs each alert with the original agency URL, the full agency name, and a timestamp so you can verify the notice against the primary source before acting on it. Tags on this item (drug-shortage, fda, medication, Dextrose Monohydrate 50% Injection) map to related alerts in the same area of risk — browsing them together gives a clearer picture than any single notice alone, because the shape of an ongoing issue only becomes visible across multiple sequential alerts.

What's in Shortage

The drug in shortage is Dextrose Monohydrate 50% Injection, with brand names DEXTROSE MONOHYDRATE and DEXTROSE. It is an injection dosage form and is currently in shortage status. It falls under therapeutic categories such as Endocrinology/Metabolism, Gastroenterology, and Pediatric. The shortage was first posted on 01/13/2022 and last updated on 04/02/2026.

Which Manufacturers Are Affected

  • Amphastar Pharmaceuticals, Inc.: Limited Availability, with the product available on allocation. Presentation: Dextrose Monohydrate 50%, Injection, 25 g/50 mL (NDC 76329-3302-1). Contact information: 800-423-4136.
  • Hospira, Inc., a Pfizer Company: Available for Dextrose Monohydrate 50%, Injection, 25 g/50 mL (NDC 0409-6648-02). Contact information: 844-646-4398.
  • Hospira, Inc., a Pfizer Company: Available for Dextrose Monohydrate 50%, Injection, 25 g/50 mL (NDC 0409-7517-16). Contact information: 844-646-4398.
  • Hospira, Inc., a Pfizer Company: Unavailable for Dextrose Monohydrate 50%, Injection, 25 g/50 mL (NDC 0409-4902-34), due to discontinuation of the manufacture of the drug. Contact information: 844-646-4398.

Why There's a Shortage

The shortage is due to an increase in demand for the drug. No additional reasons were provided.

What Patients Should Do

Patients who depend on this medication should talk to their pharmacist or healthcare provider about the current availability and options. They can also contact the manufacturers directly for more information. Please remember that patients should consult their healthcare provider for any advice related to their treatment; this article does not provide medical advice.

Source

This information is from the FDA Drug Shortages Database, initially posted on 01/13/2022 and last updated on 04/02/2026.

Source: FDA Official Notice

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Frequently Asked Questions

What is this drug shortages alert about?
The FDA has reported a current shortage of Dextrose Monohydrate 50% Injection due to increased demand, affecting some manufacturers' availability.
Which agency issued this alert?
This alert was issued by FDA. The original notice is available at the source link at the bottom of this article.
How severe is this alert?
This alert is classified as "medium" severity. Stay informed and follow agency guidance.
What area is affected?
This alert affects United States. Check with FDA for the most current geographic scope.
Where can I find more drug shortages alerts?
Browse all drug shortages alerts on Areazine at areazine.com/drug-shortages/ for the latest updates from FDA and other agencies.