Peginterferon alfa-2a Injection Shortage

Source: FDA · United States

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Peginterferon alfa-2a Injection (PEGASYS) is currently in shortage, with one presentation unavailable from the sole manufacturer.

What this FDA drug-shortage notice tells you, and what most readers miss

This notice was issued by FDA on June 12, 2026 and geographically references United States. Its severity classification of "medium" signals how the issuing agency weighs the risk of harm if no action is taken — "critical" and "high" tier alerts typically carry direct consumer actions, while "medium" and "low" tend toward informational guidance or monitoring advisories. The category it belongs to — Drug Shortages — determines the regulatory framework behind it, which shapes what remedies (refunds, replacements, recalls, evacuations) are available to affected individuals and who holds statutory responsibility for enforcement.

Most readers skim a notice like this, check whether they are personally affected, and move on. The more useful lens is to read it as a data point about the issuing system: how quickly FDA detected the hazard, how precise the geographic or product-identifier scope is, and whether similar notices have clustered in the same category or region in the last 90 days. Cluster patterns frequently precede a broader regulatory action — a single localized FDA drug-shortage notice is isolated; three of them within a quarter often indicate a supply-chain, infrastructure, or seasonal driver that will keep producing notices until something structural changes.

For decision-making, Areazine pairs each alert with the original agency URL, the full agency name, and a timestamp so you can verify the notice against the primary source before acting on it. Tags on this item (drug-shortage, fda, medication, Peginterferon alfa-2a) map to related alerts in the same area of risk — browsing them together gives a clearer picture than any single notice alone, because the shape of an ongoing issue only becomes visible across multiple sequential alerts.

What's in Shortage

Peginterferon alfa-2a Injection (brand name: PEGASYS) is listed as a current shortage. The dosage form is Injection and it belongs to the therapeutic category Antiviral. The shortage was first posted on 01/24/2025 and last updated on 06/01/2026.

Which Manufacturers Are Affected

  • pharmaand GmbH (pharma&): Available for Pegasys, Injection, 180 ug/.5 mL (NDC 82154-0451-4). Contact: 800-506-8501, email: medinfo.us@pharmaand.com
  • pharmaand GmbH (pharma&): Unavailable for Pegasys, Injection, 180 ug/1 mL (NDC 82154-0449-1). Product replenishment timeline to be confirmed sometime in Q1 2027 or earlier. Contact: 800-506-8501, email: medinfo.us@pharmaand.com

Why There's a Shortage

No specific reason for the shortage was provided in the source data.

What Patients Should Do

Patients who depend on this medication should talk to their pharmacist about current availability. They may also contact the manufacturer directly using the information above. Always consult your healthcare provider before making any changes to your treatment. This article does not provide medical advice.

Source

FDA Drug Shortage Database

Original source: FDA Official Notice ↗

All Drug Shortages →

Frequently Asked Questions

Common questions about this FDA drug-shortage notice.

What is this FDA drug-shortage notice about?
Peginterferon alfa-2a Injection (PEGASYS) is currently in shortage, with one presentation unavailable from the sole manufacturer.
Which agency issued this alert?
This alert was issued by FDA. The original notice is available at the source link at the bottom of this article.
How severe is this alert?
This alert is classified as "medium" severity. Stay informed and follow agency guidance.
What area is affected?
This alert affects United States. Check with FDA for the most current geographic scope.
Where can I find more Drug Shortages updates?
Browse the full Drug Shortages feed on Areazine at areazine.com/drug-shortages/ for the latest updates from FDA and other agencies.