Morphine Sulfate Injection Shortage: Updates on Availability and Manufacturer Status

Source: FDA · United States

Areazine synthesizes this FDA drug-shortage notice directly from FDA's official public data feed. See our methodology for full source attribution and refresh cadence.

The FDA reports a current shortage of Morphine Sulfate Injection due to increased demand, with several presentations from Fresenius Kabi USA currently unavailable.

What this FDA drug-shortage notice tells you, and what most readers miss

This notice was issued by FDA on April 6, 2026 and geographically references United States. Its severity classification of "medium" signals how the issuing agency weighs the risk of harm if no action is taken - "critical" and "high" tier alerts typically carry direct consumer actions, while "medium" and "low" tend toward informational guidance or monitoring advisories. The category it belongs to - Drug Shortages - determines the regulatory framework behind it, which shapes what mitigations (alternative therapies, allocation timelines, manufacturer guidance) are available and which agency holds oversight.

Most readers skim a notice like this, check whether they are personally affected, and move on. The more useful lens is to verify its scope, source, and timestamp, then compare related notices without assuming that one record proves a broader trend.

Areazine pairs this record with the original agency URL so you can check the primary source before acting. Its related labels are drug-shortage, fda, medication, MorphineSulfate.

What's in Shortage

Morphine Sulfate Injection (Brand Name: MORPHINE SULFATE) is currently listed as in shortage. This medication is categorized under Analgesia/Addiction and is provided in an injection dosage form. The shortage status is currently active.

Which Manufacturers Are Affected

Fresenius Kabi USA, LLC is the manufacturer reported in the current database update. Availability varies significantly by specific presentation:

  • Morphine Sulfate, Injection, 5 mg/1 mL (NDC 63323-455-01): Unavailable. Not available at this time.
  • Morphine Sulfate, Injection, 4 mg/1 mL (NDC 76045-005-11): Available. Check wholesalers for inventory.
  • Morphine Sulfate, Injection, 2 mg/1 mL (NDC 63323-452-01): Unavailable. Next release not available at this time. Check wholesalers for inventory.
  • Morphine Sulfate, Injection, 2 mg/1 mL (NDC 76045-004-11): Unavailable. Next release expected February 2026. Check wholesalers for inventory.
  • Morphine Sulfate, Injection, 10 mg/1 mL (NDC 63323-451-01): Unavailable. Next release not available at this time.
  • Morphine Sulfate, Injection, 4 mg/1 mL (NDC 63323-454-01): Available. Check wholesalers for inventory.

For more information, Fresenius Kabi USA, LLC can be contacted at 888-386-1300.

Why There's a Shortage

The FDA indicates that the primary reason for this shortage is a demand increase for the drug.

What Patients Should Do

If you are affected by this shortage, please take the following steps:

  • Consult your healthcare provider: Discuss your treatment options and any concerns regarding the availability of your medication. Do not make any changes to your treatment plan without medical supervision.
  • Talk to your pharmacist: Pharmacists often have the most up-to-date information regarding local stock and can check with various wholesalers.
  • Contact the manufacturer: You may use the contact information provided above to inquire about supply timelines.

Disclaimer: This article is for informational purposes only and does not constitute medical advice. Patients should always consult with their healthcare provider for medical guidance.

Source

Attribution: FDA Drug Shortage Database Initial Posting Date: 10/31/2017 Last Updated: 02/05/2026

Original source: FDA Official Notice ↗

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Frequently Asked Questions

Common questions about this FDA drug-shortage notice.

What is this FDA drug-shortage notice about?
The FDA reports a current shortage of Morphine Sulfate Injection due to increased demand, with several presentations from Fresenius Kabi USA currently unavailable.
Which agency issued this alert?
This alert was issued by FDA. The original notice is available at the source link at the bottom of this article.
How severe is this alert?
This alert is classified as "medium" severity. Stay informed and follow agency guidance.
What area is affected?
This alert affects United States. Check with FDA for the most current geographic scope.
Where can I find more Drug Shortages updates?
Browse the full Drug Shortages feed on Areazine at areazine.com/drug-shortages/ for the latest updates from FDA and other agencies.