Sikeston vs Cape Girardeau

Side-by-side comparison of Sikeston, MO and Cape Girardeau, MO — population, economics, education, health, hospitals, climate, and cost of living from official U.S. government data.

Reading a Sikeston vs Cape Girardeau comparison — what matters, what doesn't

Sikeston (16K residents in Missouri) and Cape Girardeau (39K residents in Missouri) differ first on the three numbers nearly every comparison starts with: median household income ($62,782 vs $68,464), median home value ($154,400 vs $220,700), and median rent ($873 vs $881 per month). Those three are highly correlated within a region but often decouple across regions because they respond to different levers — income tracks the local job market, home values track housing supply plus interest-rate pressure, and rent tracks short-run vacancy. Comparing all three at once is how you spot whether a city is "expensive because people earn a lot" or "expensive despite what they earn."

The second layer is the layer most headline comparisons skip. Poverty rate (12.8% vs 13.9%) and unemployment (2.9% vs 2.3%) describe the distribution under the median, which two cities with similar averages can present very differently. The share with a bachelor's degree or higher (22.1% vs 33.1%) is the single best proxy for income trajectory over the next decade. On healthcare, CMS Hospital Compare credits Sikeston with 1 hospital (avg rating 2/5) vs Cape Girardeau's 3 (avg 2/5).

Areazine renders each row with a national-average tick mark precisely so you can tell in one glance whether both cities are above/below the U.S. norm (they often are — cities with active residential markets self-select for certain profiles) rather than focusing on which is "better." For life decisions — where to relocate, where to retire, where to enroll a child in school — pair this page with the individual city profiles below, where health indicators, hospital ratings, school counts, and climate normals appear in full rather than as the compressed single row you see here.

Sikeston
Missouri
Pop: 16K
Income: $62,782
Home: $154,400
Cape Girardeau
Missouri
Pop: 39K
Income: $68,464
Home: $220,700

Head-to-Head Summary

Side-by-side comparison of Sikeston and Cape Girardeau on key metrics
Metric Sikeston Cape Girardeau
Population 16K 39K
Median Household Income $62,782 $68,464
Median Home Value $154,400 $220,700
Median Rent $873/mo $881/mo
Poverty Rate 12.8% 13.9%
Unemployment Rate 2.9% 2.3%
Bachelor's Degree+ 22.1% 33.1%

Population

Source: U.S. Census Bureau ACS 2022 (5-year)
Population
16K
Population
39K
Median Age
39.7 yrs
Median Age
37.1 yrs
10-Year Pop Growth
-3%
10-Year Pop Growth
+8%

Economics

Source: U.S. Census Bureau ACS 2022 (5-year)
Median Household Income
$62,782
Median Household Income
$68,464
Median Home Value
$154,400
Median Home Value
$220,700
Median Rent
$873
Median Rent
$881
Poverty Rate
12.8%
Poverty Rate
13.9%
Unemployment Rate
2.9%
Unemployment Rate
2.3%
10-Year Income Growth
+54%
10-Year Income Growth
+47%

Education & Work

Source: U.S. Census Bureau ACS 2022 (5-year)
Bachelor's Degree or Higher
22.1%
Bachelor's Degree or Higher
33.1%
Work From Home
4.4%
Work From Home
9%
Public Transit
0%
Public Transit
0.2%

Health (CDC PLACES)

Source: CDC PLACES 2023
Frequent Mental Distress
18.2%
Frequent Mental Distress
17.9%
Obesity
38.1%
Obesity
34.7%
Physical Inactivity
36.3%
Physical Inactivity
28.4%
Smoking
19.2%
Smoking
14.9%
Lack of Health Insurance
9.8%
Lack of Health Insurance
8.2%

Healthcare

Source: CMS Hospital Compare 2024
Hospitals
1
Hospitals
3
Avg Hospital Rating Same
2/5
Avg Hospital Rating
2/5

Demographics

Race categories sum to 100%. Hispanic or Latino is an ethnicity that spans all race categories, shown separately per Census Bureau methodology.

Sikeston Population
Race
White 81.7%
African American 9.2%
Asian 0.1%
Two or More Races 6.4%
Cape Girardeau Population
Race
White 84.6%
African American 7.4%
Asian 1.6%
Two or More Races 3.5%

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Data Sources

Population and economic data from the Census Bureau American Community Survey (2022 5-year estimates). Health data from the CDC PLACES (2023). Hospital data from CMS Hospital Compare (2024). Climate data from NOAA Climate Normals (1991–2020). Cost of living from BEA Regional Price Parities via FRED.

Related

City data sourced from the U.S. Census Bureau ACS, CDC PLACES, CMS Hospital Compare, NOAA Climate Normals, and BEA Regional Price Parities. See our methodology for details.