Meperidine Hydrochloride Injection (Demerol) Shortage: Most Presentations Unavailable Until 2026-2027

What’s in Shortage

Meperidine Hydrochloride Injection, commonly known by the brand name Demerol, is currently listed in a shortage status. This medication is an injection dosage form used within the Analgesia/Addiction therapeutic category. The shortage was initially posted on May 30, 2025, and was most recently updated on February 12, 2026.

Which Manufacturers Are Affected

Hospira, Inc., a Pfizer Company is the primary manufacturer listed for this shortage. Patients and providers can contact the company at 844-646-4398 for more information.

Currently Available:

• Demerol, Injection, 50 mg/1 mL (NDC 0409-1181-30)

Currently Unavailable:

• Demerol, Injection, 25 mg/1 mL (NDC 0409-1176-30): Unavailable due to manufacturing delay. Estimated recovery: June 2026.
• Demerol, Injection, 25 mg/1 mL (NDC 0409-1362-01): Unavailable. Estimated recovery: December 2027.
• Demerol, Injection, 50 mg/1 mL (NDC 0409-1178-30): Unavailable due to manufacturing delay. Estimated recovery: June 2026.
• Demerol, Injection, 50 mg/1 mL (NDC 0409-1418-01): Unavailable. Estimated recovery: December 2027.
• Demerol, Injection, 75 mg/1 mL (NDC 0409-1179-30): Unavailable due to manufacturing delay. Estimated recovery: December 2027.
• Demerol, Injection, 100 mg/1 mL (NDC 0409-1180-69): Unavailable. Estimated recovery: December 2027.

Why There’s a Shortage

The FDA lists the reason for this shortage as “Other.” According to manufacturer notes, the unavailability of several presentations is specifically attributed to a manufacturing delay.

What Patients Should Do

If you are currently prescribed Meperidine Hydrochloride Injection, please take the following steps:

• Consult Your Healthcare Provider: Discuss this shortage with your doctor to determine the best course of action for your treatment plan.
• Speak with a Pharmacist: Your pharmacist can provide information on current stock levels and whether the available 50 mg/1 mL presentation is appropriate for your needs.
• Contact the Manufacturer: For specific questions regarding supply, you may reach Hospira at 844-646-4398.

Disclaimer: This article is for informational purposes only and does not constitute medical advice. Patients should always consult with their healthcare provider or pharmacist regarding medication changes or alternatives.

Source

FDA Drug Shortage Database